| Year: | 1945–46 |
| Country: | Cyprus |
| Num Teams: | 6 |
| Dates: | 3 February 1946 – 14 April 1946 |
| Winners: | EPA (2nd title) |
| Next Season: | 1946–47 |
The 1945–46 Cypriot Cup was the ninth edition of the Cypriot Cup. A total of 6 clubs entered the competition. It began on 3 February 1946 with the quarterfinals and concluded on 14 April 1946 with the final which was held at GSP Stadium. EPA won their 2nd Cypriot Cup trophy after beating APOEL 2–1 in the final.
In the 1945–46 Cypriot Cup, participated all the teams of the Cypriot First Division.
The competition consisted of three knock-out rounds. In all rounds each tie was played as a single leg and was held at the home ground of one of the two teams, according to the draw results. Each tie winner was qualifying to the next round. If a match was drawn, extra time was following. If extra time was drawn, there was a replay match.
| width=25% align="right" | Team 1 | width=22% align="center" | Result | width=30% align="left" | Team 2 |
|---|---|---|---|---|---|
| 2 - 2, 5 - 6 | Pezoporikos Larnaca (A) | ||||
| (A) APOEL | 9 - 0 | Lefkoşa Türk Spor Kulübü (A) | |||
| (A) EPA Larnaca | Bye | ||||
| (A) Olympiakos Nicosia | Bye | ||||
| width=25% align="right" | Team 1 | width=22% align="center" | Result | width=30% align="left" | Team 2 |
|---|---|---|---|---|---|
| (A) APOEL | 4 - 0 | Olympiakos Nicosia (A) | |||
| (A) EPA Larnaca | 2 - 1 | Pezoporikos Larnaca (A) | |||