| 1945–46 Copa Federación de España | |
| Country: | Spain |
| Winners: | Alavés |
| Second: | Sueca |
| Matches: | 440 |
| Goals: | 1849 |
| Prev Season: | 1944–45 |
| Next Season: | 1950–51 |
The 1945–46 Copa Federación de España was the second staging (old competition) of the Copa Federación de España, a knockout competition for Spanish football clubs.
The competition began on 10 February 1946 and ended with the final on 20 June 1946, where Alavés became champion after defeating Sueca.