| Competition: | Primera División |
| Season: | 1944–45 |
| Winners: | Barcelona (2nd title) |
| Relegated: | Granada Sabadell Deportivo La Coruña |
| League Topscorer: | Telmo Zarra (20 goals) |
| Biggest Home Win: | Castellón 8–0 Sabadell |
| Biggest Away Win: | Sabadell 0–6 Español |
| Highest Scoring: | Valencia 9–3 Murcia |
| Matches: | 182 |
| Total Goals: | 656 |
| Longest Wins: | 6 matches Atlético Bilbao Barcelona |
| Longest Losses: | 5 matches Sabadell |
| Longest Unbeaten: | 11 matches Barcelona |
| Longest Winless: | 12 matches Sabadell |
| Prevseason: | 1943–44 |
| Nextseason: | 1945–46 |
The 1944–45 La Liga was the 14th season since its establishment. Barcelona conquered their second title, 15 years after the first one in the inaugural season.
| Club | City | Stadium | |
|---|---|---|---|
| Metropolitano | |||
| San Mamés | |||
| Les Corts | |||
| El Sequiol | |||
| Riazor | |||
| Sarriá | |||
| Los Cármenes | |||
| La Condomina | |||
| Buenavista | |||
| El Molinón | |||
| Chamartín | |||
| Cruz Alta | |||
| Nervión | |||
| Mestalla |
Since this season, there was only match of the relegation play-offs. It was played at Estadio Metropolitano de Madrid.
|}
| Rank | Player | Team | Goals | |
|---|---|---|---|---|
| 1 | 20 | |||
| 2 | 18 | |||
| 3 | 17 | |||
| 4 | align=center rowspan=2 | 16 | ||
| Barcelona | ||||
| 6 | 15 | |||
| 7 | 14 | |||
| 8 | 13 | |||
| Sevilla | ||||
| 10 | Five players | 12 | ||