| Year: | 1943 |
| Team: | SMU Mustangs |
| Sport: | football |
| Conference: | Southwest Conference |
| Short Conf: | SWC |
| Record: | 2–7 |
| Conf Record: | 2–3 |
| Head Coach: | Jimmy Stewart |
| Hc Year: | 2nd |
| Captain: | Abel Gonzalez, Ray Rasor |
| Stadium: | Ownby Stadium |
The 1943 SMU Mustangs football team was an American football team that represented Southern Methodist University (SMU) as a member of the Southwest Conference (SWC) during the 1943 college football season. In their second season under head coach Jimmy Stewart, the Mustangs compiled a 2–7 record (2–3 against conference opponents) and were outscored by a total of 115 to 69.[1]
In the final Litkenhous Ratings, SMU ranked 71st among the nation's college and service teams with a rating of 75.1.[2]
The team played its home games at Ownby Stadium in the University Park suburb of Dallas.