| Election Name: | 1942 United States Senate election in Colorado |
| Country: | Colorado |
| Flag Year: | 1911 |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1936 United States Senate election in Colorado |
| Previous Year: | 1936 |
| Next Election: | 1948 United States Senate election in Colorado |
| Next Year: | 1948 |
| Election Date: | November 3, 1942 |
| Image1: | Edwin Johnson.jpg |
| Nominee1: | Ed Johnson |
| Party1: | Democratic Party (US) |
| Popular Vote1: | 174,612 |
| Percentage1: | 50.23% |
| Party2: | Republican Party (US) |
| Popular Vote2: | 170,970 |
| Percentage2: | 49.19% |
| Map Size: | 250px |
| U.S. Senator | |
| Before Party: | Democratic Party (US) |
| After Party: | Democratic Party (US) |
The 1942 United States Senate election in Colorado took place on November 3, 1942. Incumbent Democratic Senator Edwin C. Johnson was re-elected to second term over Republican Governor Ralph L. Carr.
Carr was unopposed for the Republican nomination.