The 1942 United States House of Representatives elections in South Carolina were held on November 3, 1942, to select six Representatives for two-year terms from the state of South Carolina. All six incumbents were re-elected and the composition of the state delegation remained solely Democratic.
Incumbent Democratic Congressman L. Mendel Rivers of the 1st congressional district, in office since 1941, was unopposed in his bid for re-election.
|-| | colspan=5 |Democratic hold|-
Incumbent Democratic Congressman Hampton P. Fulmer of the 2nd congressional district, in office since 1921, was unopposed in his bid for re-election.
|-| | colspan=5 |Democratic hold|-
Incumbent Democratic Congressman Butler B. Hare of the 3rd congressional district, in office since 1939, defeated former Representative John C. Taylor in the Democratic primary and was unopposed in the general election.
| Democratic primary | ||
|---|---|---|
| Candidate | Votes | % |
| 26,280 | 61.8 | |
| 16,227 | 38.2 | |
|-| | colspan=5 |Democratic hold|-
Incumbent Democratic Congressman Joseph R. Bryson of the 4th congressional district, in office since 1939, was unopposed in his bid for re-election.
|-| | colspan=5 |Democratic hold|-
Incumbent Democratic Congressman James P. Richards of the 5th congressional district, in office since 1933, defeated G.F. Patton in the Democratic primary and was unopposed in the general election.
| Democratic primary | ||
|---|---|---|
| Candidate | Votes | % |
| 24,519 | 72.4 | |
| G.F. Patton | 9,337 | 27.6 |
|-| | colspan=5 |Democratic hold|-
Incumbent Democratic Congressman John L. McMillan of the 6th congressional district, in office since 1939, won the Democratic primary and was unopposed in the general election.
| Democratic primary | ||
|---|---|---|
| Candidate | Votes | % |
| 29,629 | 67.8 | |
| C.T. McDonald | 11,495 | 26.3 |
| Fred W. Willis | 2,580 | 5.9 |
|-| | colspan=5 |Democratic hold|-