| Club: | Liverpool F.C. |
| Season: | 1942–43 |
| Manager: | George Kay |
| Stadium: | Anfield |
| League: | North Regional League |
| League Result: | 2nd & 1st |
| Cup1 Result: | 2nd Round |
| Cup1: | League War Cup |
| League Topscorer: | Cyril Done |
| Season Topscorer: | Cyril Done |
| Pattern B1: | _collar |
| Pattern So1: | _hoops_red |
| Leftarm1: | ff0000 |
| Body1: | ff0000 |
| Rightarm1: | ff0000 |
| Pattern La2: | _redborder |
| Pattern B2: | _collarred |
| Pattern Ra2: | _redborder |
| Pattern So2: | _hoops_red |
| Shorts2: | 000000 |
| Prevseason: | 1941–42 |
| Nextseason: | 1943–44 |
The 1942–43 season saw Liverpool compete in the wartime North Regional League. Some matches were also part of the League War Cup and the Lancashire Senior Cup.
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See main article: 1942–43 in English football.