| Year: | 1941 |
| Team: | Louisville Cardinals |
| Sport: | football |
| Conference: | Southern Intercollegiate Athletic Association |
| Short Conf: | SIAA |
| Record: | 4–4 |
| Conf Record: | 1–1 |
| Head Coach: | Laurie Apitz |
| Hc Year: | 6th |
| Stadium: | Maxwell Field, duPont Manual Stadium |
The 1941 Louisville Cardinals football team was an American football team that represented the University of Louisville as a member of the Southern Intercollegiate Athletic Association (SIAA) during the 1941 college football season. In their sixth season under head coach Laurie Apitz, the Cardinals compiled a 4–4 record and outscored opponents by a combined total of 143 to 140.[1]