| Election Name: | Cleveland mayoral election, 1941 |
| Country: | Cleveland |
| Type: | presidential |
| Ongoing: | no |
| Previous Year: | 1939 |
| Next Year: | 1943 |
| Election Date: | November 4, 1941 |
| Nominee1: | Frank Lausche |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 145,324 |
| Percentage1: | 60.59% |
| Nominee2: | Edward J. Blythin |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 94,534 |
| Percentage2: | 39.41% |
| Mayor | |
| Before Election: | Edward J. Blythin |
| Before Party: | Republican Party (United States) |
| After Election: | Frank Lausche |
| After Party: | Democratic Party (United States) |
The Cleveland mayoral election of 1941 saw the election of Frank Lausche, who defeated incumbent mayor Edward J. Blythin, who had assumed the office when Harold Hitz Burton resigned as mayor to take a seat in the United States Senate.