| Competition: | Serie C |
| Season: | 1940–41 |
| Promoted: | Pro Patria Fiumana Prato Pescara |
| Relegated: | many disbanded clubs |
| Prevseason: | 1939–40 |
| Nextseason: | 1941–42 |
The 1940–41 Serie C was the sixth edition of Serie C, the third highest league in the Italian football league system.