| Election Name: | 1930 Democratic Senate primary runoff in South Carolina |
| Country: | South Carolina |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | United States Senate election in South Carolina, 1924 |
| Previous Year: | 1924 |
| Next Election: | United States Senate election in South Carolina, 1936 |
| Next Year: | 1936 |
| Election Date: | September 9, 1930 |
| Image1: | Senator James F Byrnes.jpg |
| Image1 Size: | x150px |
| Nominee1: | James F. Byrnes |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 120,755 |
| Percentage1: | 50.95% |
| Image2 Size: | x150px |
| Nominee2: | Cole Blease |
| Party2: | Democratic Party (United States) |
| Popular Vote2: | 116,264 |
| Percentage2: | 49.05% |
| Map Size: | 250px |
| U.S. Senator | |
| Before Election: | Coleman Livingston Blease |
| Before Party: | Democratic Party (United States) |
| After Election: | James F. Byrnes |
| After Party: | Democratic Party (United States) |
The 1930 South Carolina United States Senate election was held on November 4, 1930, to select the U.S. Senator from the state of South Carolina. Incumbent Democratic Senator Coleman Livingston Blease was defeated in the Democratic primary by James F. Byrnes. He was unopposed in the general election to win a six-year term.
Senator Coleman Livingston Blease was opposed in the Democratic primary by former Representative James F. Byrnes. Blease was the leader in the first primary election on August 26, but in previous primary elections he had been the leader in the first primary and unable to increase his support in the runoff election. This election was no different and Byrnes won the runoff on September 9. There was no opposition to the Democratic candidate in the general election so Byrnes was elected to a six-year term in the Senate.
| Democratic Primary | ||
|---|---|---|
| Candidate | Votes | % |
| Coleman Livingston Blease | 111,989 | 46.0 |
| 92,242 | 37.8 | |
| Leon W. Harris | 39,512 | 16.2 |
| Democratic Primary Runoff | |||
|---|---|---|---|
| Candidate | Votes | % | ±% |
| James F. Byrnes | 120,755 | 50.9 | +13.1 |
| Coleman Livingston Blease | 116,264 | 49.1 | +3.1 |
|-| | colspan=5 |Democratic hold|-