| Election Name: | 1928 United States Senate election in Arizona |
| Country: | Arizona |
| Type: | Presidential |
| Ongoing: | no |
| Previous Election: | 1922 United States Senate election in Arizona |
| Previous Year: | 1922 |
| Next Election: | 1934 United States Senate election in Arizona |
| Next Year: | 1934 |
| Election Date: | November 6, 1928 |
| Nominee1: | Henry F. Ashurst |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 47,013 |
| Percentage1: | 54.25% |
| Nominee2: | Ralph H. Cameron |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 39,651 |
| Percentage2: | 45.75% |
| Map Size: | 210px |
| U.S. Senator | |
| Before Election: | Henry F. Ashurst |
| Before Party: | Democratic Party (United States) |
| After Election: | Henry F. Ashurst |
| After Party: | Democratic Party (United States) |
The 1928 United States Senate elections in Arizona took place on November 6, 1928. Incumbent Democratic U.S. Senator Henry F. Ashurst ran for reelection to a fourth term, defeating Republican nominee former U.S. Senator Ralph H. Cameron in the general election. Cameron was defeated in the previous election year, in 1926, by then-U.S. Congressman Carl T. Hayden, leading Cameron to decide to challenge Ashurst in order to return to the United States Senate.