| Year: | 1927 |
| Team: | Wyoming Cowboys |
| Sport: | football |
| Conference: | Rocky Mountain Conference |
| Short Conf: | RMC |
| Record: | 4–5 |
| Conf Record: | 1–4 |
| Head Coach: | George McLaren |
| Hc Year: | 1st |
| Captain: | None |
| Stadium: | Campus athletic grounds |
The 1927 Wyoming Cowboys football team was an American football team that represented the University of Wyoming as a member of the Rocky Mountain Conference (RMC) during the 1927 college football season. In their first season under head coach George McLaren, the Cowboys compiled a 4–5 record (1–4 against conference opponents), finished tenth in the RMC, and outscored opponents by a total of 122 to 105.[1] [2]