| Election Name: | 1927 Philadelphia mayoral election |
| Country: | Philadelphia |
| Type: | presidential |
| Ongoing: | no |
| Previous Year: | 1923 |
| Next Year: | 1931 |
| Image1: | Harry A. Mackey by Goldensky Photo (1).jpg |
| Nominee1: | Harry Arista Mackey |
| Party1: | Republican Party (United States) |
| Popular Vote1: | 296,959 |
| Percentage1: | 67.63% |
| Nominee2: | J. Hampton Moore |
| Party2: | Citizens' |
| Popular Vote2: | 128,611 |
| Percentage2: | 29.29% |
| Mayor | |
| Before Election: | W. Freeland Kendrick |
| Before Party: | Republican Party (United States) |
| After Election: | Harry Arista Mackey |
| After Party: | Republican Party (United States) |
The 1927 Philadelphia mayoral election saw Republican nominee Harry Arista Mackey defeat former Republican mayor J. Hampton Moore, who was running on the Citizens' party line.