The 1924–25 season was the 16th in the history of the Isthmian League, an English football competition.
London Caledonians were champions, winning their sixth Isthmian League title.
| Competition: | Isthmian League |
| Season: | 1924–25 |
| Winners: | London Caledonians |
| Matches: | 182 |
| Total Goals: | 730 |
| Prevseason: | 1923–24 |
| Nextseason: | 1925–26 |