| Election Name: | 1922 United States Senate election in California |
| Country: | California |
| Flag Image: | Flag of California (1911–1924).pngborder |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1916 United States Senate election in California |
| Previous Year: | 1916 |
| Next Election: | 1928 United States Senate election in California |
| Next Year: | 1928 |
| Election Date: | November 7, 1922 |
| Image1: | Hiram Johnson 2 (cropped closein 3x4).jpg |
| Nominee1: | Hiram Johnson |
| Party1: | Republican Party (US) |
| Popular Vote1: | 564,422 |
| Percentage1: | 62.17% |
| Nominee2: | William J. Pearson |
| Party2: | Democratic Party (US) |
| Popular Vote2: | 215,748 |
| Percentage2: | 23.76% |
| Image4: | Henry Clay Needham Crop.jpg |
| Nominee4: | Henry Clay Needham |
| Party4: | Prohibition Party (US) |
| Popular Vote4: | 70,748 |
| Percentage4: | 7.79% |
| Image5: | Upton Sinclair 1.jpg |
| Nominee5: | Upton Sinclair |
| Party5: | Socialist Party USA |
| Popular Vote5: | 56,982 |
| Percentage5: | 6.28% |
| Map Size: | 300px |
| U.S. Senator | |
| Before Election: | Hiram Johnson |
| Before Party: | Republican Party (United States) |
| After Election: | Hiram Johnson |
| After Party: | Republican Party (United States) |
The 1922 United States Senate election in California was held on November 7, 1922. Incumbent Republican Senator Hiram Johnson was re-elected to his second term in office.
His greatest challenge came from fellow Republican Charles C. Moore, a citrus and olive rancher.
William J. Pearson was unopposed on the ballot, but some primary voters wrote in Republicans Hiram Johnson or Charles C. Moore.