| Year: | 1921 |
| Team: | Tulsa Orange and Black |
| Sport: | football |
| Conference: | Oklahoma Intercollegiate Conference |
| Short Conf: | OIC |
| Record: | 6–3 |
| Conf Record: | 5–1 |
| Head Coach: | Francis Schmidt |
| Hc Year: | 3rd |
| Stadium: | McNulty Park |
| Prev: | 1920 |
| Next: | 1922 |
The 1921 Tulsa Orange and Black football team represented the University of Tulsa during the 1921 college football season. In their third year under head coach Francis Schmidt, the Orange and Black compiled a 6–3 record and outscored their opponents by a total of 257 to 95. The team won its first two games by scores of 92–0 over and 75–13 over the Chilocco Indian Agricultural School.[1] Schmidt was later inducted into the College Football Hall of Fame.