| Year: | 1921 |
| Team: | Tulane Green Wave |
| Sport: | football |
| Conference: | Southern Intercollegiate Athletic Association |
| Short Conf: | SIAA |
| Record: | 4–6 |
| Conf Record: | 3–3 |
| Head Coach: | Myron Fuller |
| Hc Year: | 1st |
| Off Scheme: | Single-wing |
| Captain: | James Reed |
| Stadium: | Second Tulane Stadium |
The 1921 Tulane Green Wave football team was an American football team that represented Tulane University as a member of the Southern Intercollegiate Athletic Association (SIAA) during the 1921 college football season. In its first year under head coach Myron Fuller, Tulane compiled a 4–6 record.[1]