| Team: | Evansville Crimson Giants |
| Year: | 1921 |
| Record: | 7–2–1 Overall 3–2 APFA |
| Division Place: | 6th APFA |
| Coach: | Frank Fausch |
| Stadium: | Bosse Field |
| Playoffs: | No playoffs until 1932 |
| Previous: | N/A |
| Next: | 1922 |
The 1921 Evansville Crimson Giants season was their inaugural in the young American Professional Football Association (APFA). The team finished with a 3–2 record in league play,[1] and finished in sixth place in the standings.,[2]
| Week | Date | Opponent | Result | |
|---|---|---|---|---|
| 1 | October 2 | Louisville Brecks | W 21–0 | |
| 2 | October 9 | Muncie Flyers | W 14–0 | |
| 3 | October 16 | at Hammond Pros | L 0–3 | |
| – | October 23 | New Albany Calumet Indians | W 90–0 | |
| – | October 30 | Camp Knox Officers | W 90–0 | |
| 4 | November 6 | at Green Bay Packers | L 6–43 | |
| – | November 11 | Kentucky All-Stars | W 7–0 | |
| 5 | November 27 | Cincinnati Celts | W 48–0 | |
| – | December 4 | Indianapolis Football Club | W 17–0 | |
| – | December 18 | Paducah Alumni | T 0–0 |