| Team: | Cleveland Tigers (NFL) |
| Year: | 1921 |
| Record: | 3–5–1 Overall 3–5 APFA |
| League Place: | 11th APFA |
| Coach: | Jim Thorpe |
| Stadium: | Dunn Field |
| Next: | N/A |
The 1921 Cleveland Indians season was their second completed in the young American Professional Football Association (APFA). The team improved on their previous record of 2–4–2, winning three games.[1] They finished eleventh in the league.[2]
| Week | Date | Opponent | Result | |
|---|---|---|---|---|
| 1 | October 16 | Columbus Panhandles | W 35–9 | |
| 2 | October 23 | Cincinnati Celts | W 28–0 | |
| 3 | October 30 | at Dayton Triangles | L 2–3 | |
| 4 | November 6 | at Buffalo All-Americans | L 6–10 | |
| 5 | November 13 | Canton Bulldogs | L 0–7 | |
| 6 | November 20 | at Chicago Staleys | L 7–22 | |
| 7 | December 3 | at New York Brickley Giants | W 17–0 | |
| – | December 10 | at Richmond Athletic Club | T 0–0 | |
| 8 | December 11 | at Washington Senators | L 0–7 |