| Team: | Cincinnati Celts |
| Year: | 1921 |
| Record: | 3–3 Overall 1–3 APFA |
| League Place: | T-13th APFA |
| Coach: | Mel Doherty |
| Stadium: | Traveling team |
| Previous: | none |
| No Prevseason: | true |
| Next: | none |
| No Nextseason: | true |
| No Seasonslist: | true |
The 1921 Cincinnati Celts season was their sole season in the young American Professional Football Association (APFA). The team finished 1–3,[1] and tied for thirteenth place in the league.
| Week | Date | Opponent | Result | |
|---|---|---|---|---|
| 1 | October 2 | at Akron Pros | L 0–41 | |
| 2 | October 16 | at Muncie Flyers | W 14–0 | |
| 3 | October 23 | at Cleveland Indians | L 0–28 | |
| 4 | November 6 | at Fort Wayne Pros | W 13–0 | |
| 5 | November 20 | at Middletown Miamis | W 21–14 | |
| 6 | November 27 | at Evansville Crimson Giants | L 0–48 |