| Year: | 1921 |
| Team: | Chattanooga Moccasins |
| Sport: | football |
| Conference: | Southern Intercollegiate Athletic Association |
| Short Conf: | SIAA |
| Record: | 4–6 |
| Conf Record: | 2–4 |
| Head Coach: | Silas Williams |
| Hc Year: | 3rd |
| Captain: | Corbett Owens |
| Stadium: | Chamberlain Field |
The 1921 Chattanooga Moccasins football team represented the University of Chattanooga (now known as the University of Tennessee at Chattanooga) as a member of the Southern Intercollegiate Athletic Association during the 1921 college football season. In their third season under head coach Silas Williams, the Moccasins completed its 10-game schedule with a record of 4 wins and 6 losses.[1]