| Team: | Akron Pros |
| Year: | 1921 |
| Record: | 8–3–1 |
| Division Place: | 3rd APFA |
| Coach: | Fritz Pollard and Elgie Tobin |
| Stadium: | League Park |
| Playoffs: | No playoffs until 1932 |
The 1921 Akron Pros season was their second completed in the young American Professional Football Association (APFA). The team failed to improve on their previous output of 8–0–3, losing three games.[1] They finished third in the league.
| Week | Date | Opponent | Result | |
|---|---|---|---|---|
| 1 | September 25 | Columbus Panhandles | W 14–0 | |
| 2 | October 2 | Cincinnati Celts | W 41–0 | |
| 3 | October 9 | at Chicago Cardinals | W 23–0 | |
| 4 | October 16 | at Detroit Tigers | W 20–0 | |
| 5 | October 23 | at Canton Bulldogs | W 3–0 | |
| 6 | October 30 | Rochester Jeffersons | W 19–0 | |
| 7 | November 6 | at Columbus Panhandles | W 21–0 | |
| 8 | November 13 | at Buffalo All-Americans | T 0–0 | |
| 9 | November 20 | at Dayton Triangles | L 0–3 | |
| 10 | November 24 | Canton Bulldogs | L 0–14 | |
| 11 | December 3 | at Buffalo All-Americans | L 0–14 | |
| 12 | December 4 | at Chicago Cardinals | W 7–0 |