| Election Name: | 1918 United States Senate election in Colorado |
| Country: | Colorado |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1913 United States Senate election in Colorado |
| Previous Year: | 1913 |
| Next Election: | 1924 United States Senate election in Colorado |
| Next Year: | 1924 |
| Election Date: | November 5, 1918 |
| Image1: | File:Lawrence Cowle Phipps2.jpg |
| Nominee1: | Lawrence C. Phipps |
| Party1: | Republican Party (United States) |
| Popular Vote1: | 107,726 |
| Percentage1: | 49.49% |
| Nominee2: | John F. Shafroth |
| Party2: | Democratic Party (United States) |
| Popular Vote2: | 104,347 |
| Percentage2: | 47.94% |
| Map Size: | 250px |
| U.S. Senator | |
| Before Election: | John F. Shafroth |
| Before Party: | Democratic Party (United States) |
| After Election: | Lawrence C. Phipps |
| After Party: | Republican Party (United States) |
The 1918 United States Senate election in Colorado took place on November 5, 1918. It was the second direct U.S. Senate election in Colorado following the ratification of the Seventeenth Amendment, and the first for the Class 2 Senate seat. Democratic senator John F. Shafroth ran for re-election to a second term, and was opposed by Denver businessman Lawrence C. Phipps, the Republican nominee, in the general election. As Republicans made gains nationwide, they performed well in Colorado, too, and Phipps unseated Shafroth by a thin margin.