| Year: | 1918 |
| Team: | Centre Colonels |
| Sport: | football |
| Conference: | Independent |
| Record: | 4–0 |
| Head Coach: | Charley Moran |
| Hc Year: | 2nd |
| Asst Coach1: | Robert L. Myers |
| Off Scheme: | Single-wing |
| Captain: | Matty Bell |
| Stadium: | Cheek Field |
| Prev: | 1917 |
| Next: | 1919 |
The 1918 Centre Colonels football team represented Centre College in the 1918 college football season. The season started late due to the flu epidemic. The game on November 16 with University of Kentucky was cancelled for the same reason.
| Matty Bell | end | North Side H. S. | 163 | 19 | ||||
| Ashley Blevins | guard | |||||||
| Ben Cregor | guard | Springfield, KY | 5'11" | 175 | 19 | |||
| Bill James | tackle | Fort Worth, TX | North Side H. S. | 169 | 20 | |||
| Sully Montgomery | tackle | Fort Worth, TX | North Side H. S. | 6'3" | 210 | 17 | ||
| Red Weaver | center | Fort Worth, TX | North Side H. S. | 5'10" | 158 | 20 | ||
| Edwin Whitnell | end | Fulton, KY | Fulton H. S. | 160 | 18 |
| Norris Armstrong | halfback | Fort Smith, AR | Fort Smith H. S. | 5'10" | 154 | 20 | ||
| Allen Davis | halfback | Danville, KY | 148 | 19 | ||||
| Bo McMillin | quarterback | Fort Worth, TX | North Side H. S. | 5'9" | 175 | 20 | ||
| Red Roberts | fullback | Somerset, KY | Somerset H. S. | 6'2" | 193 | 18 |
| Tom Moran | back | Nashville, TN | 5'8" | 175 | 18 | |||
| Joe Murphy | back | Columbus, OH | East H. S. | 130 | 19 |
| John Copper | |
| Robert Ford | |
| Herbert Lancaster | |
| A. W. Price | |
| L. W. Walker | |
| C. L. Williams, |