| Year: | 1915 |
| Team: | Central University |
| Sport: | football |
| Conference: | Southern Intercollegiate Athletic Association |
| Short Conf: | SIAA |
| Record: | 3–5–1 |
| Conf Record: | 0–3–1 |
| Head Coach: | Orville B. Littick |
| Hc Year: | 1st |
| Stadium: | Cheek Field |
The 1915 Central University football team represented Central University of Kentucky (now known as Centre College) as a member the Southern Intercollegiate Athletic Association (SIAA) during the 1915 college football season. Led by first-year head coach Orville B. Littick, the team compiled an overall record of 3–5–1, with a mark of 0–3–1 in conference play.