| Competition: | Uruguayan Primera División |
| Season: | 1910 (10th) |
| Winners: | River Plate |
| Relegated: | French |
| Matches: | 72 |
| Total Goals: | 206 |
| Prevseason: | 1909 |
| Nextseason: | 1911 |
The Uruguayan Championship 1910 was the tenth official championship of Uruguayan football history.
The tournament consisted of a two-wheel championship of all against all. It involved nine teams, and the champion was River Plate F.C.
| Team | City | Stadium | Capacity | Foundation | Seasons | Consecutive seasons | Titles | 1909 | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Bristol | Montevideo | 2 | 2 | align=center | - | 7th | ||||||
| CURCC | Montevideo | 28 September 1891 | 9 | 9 | 4 | 2nd | ||||||
| Central | Montevideo | 5 January 1905 | 1 | 1 | align=center | - | 6th | |||||
| Dublin | Montevideo | 2 | 2 | align=center | - | 5th | ||||||
| French | Montevideo | 2 | 2 | align=center | - | 10th | ||||||
| Libertad | Montevideo | align=center | - | align=center | - | align=center | - | align=center | - | |||
| Nacional | Montevideo | Gran Parque Central | 7,000 | 14 May 1899 | 8 | 8 | 2 | 4th | ||||
| Oriental | Montevideo | 1 | 1 | align=center | - | 11th | ||||||
| River Plate | Montevideo | 1897 | 3 | 3 | 1 | 3rd | ||||||
| Montevideo Wanderers | Montevideo | 15 August 1902 | 6 | 6 | 2 | 1st |