| Year: | 1910 |
| Prev Season: | 1909 |
| Next Season: | 1911 |
| Top Points: | Arthur McCabe (53) |
| Top Goals: | Arthur Conlin (18) |
| Top Tries: | Arthur McCabe (17) |
| Stadium: | Royal Agricultural Society Showground |
| Captain2: | Arthur Hennessy |
| Captain: | John Leveson |
| League: | NSWRFL |
| Points Against: | 109 |
| Points For: | 326 |
| League Losses: | 3 |
| League Draws: | 0 |
| League Wins: | 11 |
| Playoff Result: | Runners-up |
| League Rank: | 2nd (out of 8) |
The 1910 South Sydney season was the 3rd in the club's history. The club competed in the New South Wales Rugby Football League Premiership (NSWRFL), finishing the season as runners-up.
| Team | Pld | W | D | L | PF | PA | PD | Pts | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Newtown | 14 | 11 | 1 | 2 | 260 | 92 | +170 | 23 | |
| 2 | South Sydney | 14 | 11 | 0 | 3 | 326 | 109 | +217 | 22 | |
| 3 | Eastern Suburbs | 14 | 9 | 2 | 3 | 248 | 116 | +132 | 20 | |
| 4 | Balmain | 14 | 8 | 0 | 6 | 153 | 190 | -37 | 16 | |
| 5 | Glebe | 14 | 6 | 0 | 8 | 175 | 194 | -19 | 12 | |
| 6 | Annandale | 14 | 5 | 1 | 8 | 145 | 200 | -55 | 11 | |
| 7 | North Sydney | 14 | 3 | 0 | 11 | 146 | 283 | -137 | 6 | |
| 8 | Western Suburbs | 14 | 1 | 0 | 13 | 115 | 386 | -271 | 2 |
| Round | Opponent | Result | Score | Date | Venue | Crowd | Ref | |
|---|---|---|---|---|---|---|---|---|
| 1 | Balmain | Win | 13 – 5 | Saturday 30 April | Birchgrove Oval | 6,000 | [1] | |
| 2 | Glebe | Win | 10 – 3 | Saturday 14 May | Wentworth Park | 2,000 | [2] | |
| 3 | Eastern Suburbs | Win | 14 – 10 | Saturday 21 May | Royal Agricultural Society Showground | 5,000 | [3] | |
| 4 | Newtown | Loss | 7 – 12 | Saturday 28 May | Royal Agricultural Society Showground | 15,000 | [4] | |
| 5 | North Sydney | Loss | 27 – 21 | Saturday 25 June | North Sydney Oval | 2,000 | [5] | |
| 6 | Western Suburbs | Win | 32 – 13 | Saturday 2 July | Metters Stadium | 1,000 | [6] | |
| 7 | Annandale | Win | 34 – 8 | Saturday 16 July | Royal Agricultural Society Showground | 3,000 | [7] | |
| 8 | Western Suburbs | Win | 67 – 0 | Saturday 23 July | Royal Agricultural Society Showground | 500 | [8] | |
| 9 | North Sydney | Win | 53 – 4 | Saturday 30 July | Royal Agricultural Society Showground | 600 | [9] | |
| 10 | Newtown | Win | 15 – 8 | Saturday 13 August | Royal Agricultural Society Showground | 14,000 | [10] | |
| 11 | Annanadale | Win | 19 – 2 | Saturday 20 August | Royal Agricultural Society Showground | 2,500 | [11] | |
| 12 | Eastern Suburbs | Loss | 8 – 3 | Saturday 27 August | Royal Agricultural Society Showground | 12,000 | [12] | |
| 13 | Glebe | Win | 22 – 2 | Saturday 3 September | Wentworth Park | 1,500 | [13] | |
| 14 | Balmain | Win | 16 – 7 | Saturday 10 September | Birchgrove Oval | 3,000 | [14] |
Newtown 4 (Goals: Charles Russell 2)
drew with
South Sydney 4 (Goals: Jim Davis 2)
(Newtown finished as premiers as they had been minor premiers)
On July 23, Souths recorded a 67–0 win over Western Suburbs in Round 8. This remains the club record for largest win margin in a game. It is also the largest win margin performed by Souths against a defunct NSWRL/NRL team (assuming the existing Wests Tigers are a separate entity to the Western Suburbs club).[15]