| Election Name: | 1910 South Dakota gubernatorial election |
| Country: | South Dakota |
| Flag Year: | 1909 |
| Type: | Presidential |
| Ongoing: | no |
| Previous Election: | 1908 South Dakota gubernatorial election |
| Previous Year: | 1908 |
| Next Election: | 1912 South Dakota gubernatorial election |
| Next Year: | 1912 |
| Election Date: | November 8, 1910 |
| Nominee1: | Robert S. Vessey |
| Party1: | Republican Party (United States) |
| Popular Vote1: | 61,744 |
| Percentage1: | 58.35% |
| Nominee2: | Chauncey L. Wood |
| Party2: | Democratic Party (United States) |
| Popular Vote2: | 37,983 |
| Percentage2: | 35.90% |
| Map Size: | 250px |
| Governor | |
| Before Election: | Robert S. Vessey |
| Before Party: | Republican Party (United States) |
| After Election: | Robert S. Vessey |
| After Party: | Republican Party (United States) |
The 1910 South Dakota gubernatorial election was held on November 8, 1910. Incumbent Republican Governor Robert S. Vessey ran for re-election to a second term. He faced two serious competitors in the Republican primary: colorful disbarred attorney George W. Egan and former Governor Samuel H. Elrod, and won the primary only with a narrow plurality. In the general election, he faced Democratic nominee Chauncey L. Wood, the Mayor of Rapid City. He improved on his margin from 1908, defeating Wood in a landslide.
Primary elections were held on June 7, 1910.