| Year: | 1910 |
| Team: | Sewanee Tigers |
| Sport: | football |
| Conference: | Southern Intercollegiate Athletic Association |
| Short Conf: | SIAA |
| Record: | 8–2 |
| Conf Record: | 3–1 |
| Head Coach: | Harris G. Cope |
| Hc Year: | 2nd |
| Captain: | Aubrey Lanier |
| Stadium: | Hardee Field |
The 1910 Sewanee Tigers football team represented during the 1910 college football season as a member of the Southern Intercollegiate Athletic Association (SIAA). The Tigers were led by head coach Harris G. Cope in his second season and finished with a record of eight wins and two losses (8–2 overall, 3–1 in the SIAA).
| Frank Faulkinberry | tackle | 6'4" | 198 | 23 | |||
| Frank Gailor | guard | ||||||
| Jenks Gillem | end | ||||||
| Frank Gillespie | end | ||||||
| Frank Juhan | center | West Texas Military Academy | 5'11" | 160 | 23 | ||
| R. N. MacCallum | tackle | Mt. Vernon High | 22 | ||||
| James Stoney | guard |
| Chigger Browne | quarterback | 5'8" | 125 | 22 | |||
| Aubrey Lanier | halfback | 5'10" | 170 | 22 | |||
| John Myers | halfback | ||||||
| Guy Ward | fullback |
| Edmund Armes | |
| A. G. Bramwell | |
| Carlton Bowden | |
| Ben Cameron | |
| Ivan Cochran | |
| R. W. Easley | |
| J. H. Gordon | |
| Randolph Leigh | |
| A. P. Magwood | |
| Hugh McKnight | |
| Jack Swain |