| Year: | 1910 |
| Team: | LSU Tigers |
| Sport: | football |
| Conference: | Southern Intercollegiate Athletic Association |
| Short Conf: | SIAA |
| Record: | 1–5 |
| Conf Record: | 1–3 |
| Head Coach: | John W. Mayhew |
| Hc Year: | 2nd |
| Captain: | John Seip |
| Stadium: | State Field |
The 1910 LSU Tigers football team represented Louisiana State University (LSU) as a member of the Southern Intercollegiate Athletic Association (SIAA) during the 1910 college football season. John W. Mayhew in his second and final season as head coach, the Tigers compiled an overall record of 1–5 with a mark of 1–3 in SIAA play.
| No. | Player | Position | Height | Weight | Hometown | High School | |
|---|---|---|---|---|---|---|---|
| - | C. P. Bond | Halfback | - | - | - | - | |
| - | - | - | - | Houma, LA | - | ||
| - | W. Morton Evans | End, Halfback | - | - | Baton Rouge, LA | - | |
| - | Marshall L. Gosserand | - | - | - | New Roads, LA | - | |
| - | J. O. Hall | - | - | - | Lake Charles, LA | - | |
| - | M. R. Hammond | - | - | - | Jennings, LA | - | |
| - | Halfback | - | - | Jessup, PA | - | ||
| - | C. Y. Martin | Guard | - | - | Bowie, LA | - | |
| - | Barney G. McHenry | - | - | - | Monroe, LA | - | |
| - | William M. Pollock | - | - | - | Bernice, LA | - | |
| - | John H. Potts | End | - | - | Baton Rouge, LA | - | |
| - | Charles S. Reily | Tackle | - | - | Clinton, LA | - | |
| - | End | - | - | Allentown, PA | - | ||
| - | Arthur J. Thomas | - | - | - | Baton Rouge, LA | - |