| Year: | 1908 |
| Team: | Washington University |
| Sport: | football |
| Conference: | Missouri Valley Conference |
| Short Conf: | MVC |
| Record: | 4–4–1 |
| Conf Record: | 0–2 |
| Head Coach: | Frank Cayou |
| Hc Year: | 1st |
| Stadium: | Francis Field |
The 1908 Washington University Pikers football team represented Washington University in St. Louis as a member of the Missouri Valley Conference (MVC) during the 1908 college football season. Led by first-year head coach Frank Cayou, the team compiled an overall record of 4–4–1 with a mark of 0–2 in conference play, placing sixth in the MVC. Washington University played home games at Francis Field in St. Louis.