List of champions of the 1906 U.S. National Championships tennis tournament (now known as the US Open). The men's tournament was held from August 21 to August 29 on the outdoor grass courts at the Newport Casino in Newport, Rhode Island. The women's tournament was held from June 19 to June 23 on the outdoor grass courts at the Philadelphia Cricket Club in Philadelphia, Pennsylvania. It was the 26th U.S. National Championships and the second Grand Slam tournament of the three played that year.
See main article: 1906 U.S. National Championships – Men's singles. 
William Clothier defeated Beals Wright 6–3, 6–0, 6–4
See main article: 1906 U.S. National Championships – Women's singles. Helen Homans defeated Maud Barger-Wallach 6–4, 6–3
Holcombe Ward (USA) / Beals Wright (USA) defeated Fred Alexander (USA) / Harold Hackett (USA) 6–3, 3–6, 6–3, 6–3
Ann Burdette Coe (USA) / Ethel Bliss Platt (USA) defeated Helen Homans (USA) / Clover Boldt (USA) 6–4, 6–4 [1]
Sarah Coffin (USA) / 
Edward Dewhurst (AUS) defeated Margaret Johnson (USA) / J.B. Johnson (USA) 6–3, 7–5 [1]