| Season: | 1900–01 |
| Competition: | Swiss Serie A |
| Prevseason: | 1899–1900 |
| Nextseason: | 1901–02 |
The 1900–01 Swiss Serie A season was the 1900–01 season of the Swiss national football league championship.
The 1900–01 Swiss Serie A was divided into two groups, an east and a west group. The east group had three teams from Zürich, Grasshopper Club Zürich, FC Zürich, Fire Flies Zürich and three teams from Basel, FC Basel, Old Boys and Fortuna Basel. There were four teams in the west group, FC La Chaux-de-Fonds, Servette Genf, FC Neuchâtel and FC Bern. From the east group the Grasshoppers qualified themselves for the finals against FC Bern who were the winners of the east group.
The final was played on 31 March 1901 in Aarau, but a player from the Grasshopper Club was not-qualified and the result was voided and replayed. The replay was on 14 April, again in Aarau, and the Grasshopper Club won 2-0 and became Swiss Champions.
|colspan="3" style="background-color:#D0D0D0" align=center|31 March 1901|}The final was voided and repeated because the Grasshopper fielded an unqualified player.
Grasshopper Club Zürich won the championship.