| Year: | 1899 |
| Team: | Guilford Quakers |
| Sport: | football |
| Conference: | Independent |
| Record: | 2–1–1 |
| Head Coach: | Herbert C. Petty |
| Hc Year: | 1st |
The 1899 Guilford Quakers football team represented Guilford College as an independent during the 1897 college football season. Led by head coach Herbert C. Petty, the Quakers compiled a record of 2–1–1.