The 1888 Gower by-election was a parliamentary by-election held for the British House of Commons constituency of Gower in South Wales on 27 March 1888.
The vacancy resulted from the death of the sitting member, Frank Ash Yeo, who had held the seat since it was formed in 1885.
David Randell was elected by a small majority, defeating the Conservative landowner, John Dillwyn-Llewellyn.