| Election Name: | Buffalo mayoral election, 1881 |
| Type: | presidential |
| Ongoing: | no |
| Previous Year: | 1879 |
| Next Year: | 1883 (special) |
| Nominee1: | Grover Cleveland |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 15,120 |
| Percentage1: | 56.74% |
| Nominee2: | Milton Beebe |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 11,528 |
| Percentage2: | 43.26% |
| Mayor | |
| Before Election: | Alexander Brush |
| Before Party: | Republican Party (United States) |
| After Election: | Grover Cleveland |
| After Party: | Democratic Party (United States) |
The Buffalo mayoral election of 1881 saw the election of former Erie County Sheriff Grover Cleveland, who defeated architect and alderman Milton Beebe by what was considered a broad margin.[1]
Cleveland would not serve out his entire term as mayor, as he would be subsequently elected Governor of New York the following year.