| Election Name: | 1880 West Virginia gubernatorial election |
| Type: | presidential |
| Previous Election: | 1876 West Virginia gubernatorial election |
| Previous Year: | 1876 |
| Next Election: | 1884 West Virginia gubernatorial election |
| Next Year: | 1884 |
| Ongoing: | no |
| Election Date: | October 12, 1880 |
| Nominee1: | Jacob B. Jackson |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 60,991 |
| Percentage1: | 51.31% |
| Nominee2: | George Cookman Sturgiss |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 44,855 |
| Percentage2: | 37.73% |
| Nominee3: | N. B. French |
| Party3: | Greenback Party |
| Popular Vote3: | 13,027 |
| Percentage3: | 10.96% |
| Governor | |
| Before Election: | Henry M. Mathews |
| Before Party: | Democratic Party (United States) |
| After Election: | Jacob B. Jackson |
| After Party: | Democratic Party (United States) |
The 1880 West Virginia gubernatorial election took place on October 12, 1880, to elect the governor of West Virginia.