The 1880 Radnor Boroughs by-election was a parliamentary by-election held for the House of Commons constituency of Radnor Boroughs in Wales on 17 May 1880.
The by-election was caused by the resignation of the sitting Liberal MP, Spencer Cavendish who was also elected MP for North East Lancashire and opted to sit there, causing a by-election.
Two candidates nominated.
The Liberal Party nominated former Acting Governor of Grenada Samuel Williams.
The Conservative Party nominated a soldier, Cecil Alfred Tufton Otway.[1]