Pennsylvania gained three seats in reapportionment following the 1820 United States census. Pennsylvania elected its members October 8, 1822.
| District | Incumbent | This race | ||||||
|---|---|---|---|---|---|---|---|---|
| Member | Party | First elected | Results | Candidates[1] | ||||
| None (District created) | New seat. New member elected. Federalist gain. | nowrap | ||||||
| Joseph Hemphill | Federalist | 1800 1802 (Lost) 1818 | Incumbent re-elected. | nowrap | ||||
| Thomas Forrest | Federalist | 1822 (Special) | Incumbent lost re-election. New member elected. Democratic-Republican gain. | nowrap | ||||
| James Buchanan | Federalist | 1820 | Incumbent re-elected. | |||||
| William Darlington | Democratic-Republican | 1814 1816 (Lost) 1818 | Incumbent lost re-election. New member elected. Federalist gain. | |||||
| Samuel Edwards | Federalist | 1818 | Incumbent re-elected. | |||||
| None (District created) | New seat. New member elected. Democratic-Republican gain. | nowrap | ||||||
| John Phillips | Federalist | 1820 | Incumbent lost re-election. New member elected. Democratic-Republican gain. | nowrap | ||||
| Ludwig Worman | Federalist | 1820 | Incumbent lost re-election. New member elected. Democratic-Republican gain. Incumbent then died October 17, 1822, and winner was also elected December 10, 1822, to begin term early. | |||||
| None (District created) | New seat. New member elected. Democratic-Republican gain. | |||||||
| Samuel D. Ingham | Democratic-Republican | 1822 (Special) | Incumbent re-elected. | |||||
| Thomas J. Rogers | Democratic-Republican | 1818 (Special) | Incumbent re-elected. | |||||
| None (District created) | New seat. New member elected. Federalist gain. | |||||||
| None (District created) | New seat. New member elected. Democratic-Republican gain. | |||||||
| None (District created) | New seat. New member elected. Democratic-Republican gain. | |||||||
| James S. Mitchell | Democratic-Republican | 1820 | Incumbent re-elected. | nowrap | ||||
| John Findlay | Democratic-Republican | 1821 (Special) | Incumbent re-elected. | |||||
| James McSherry | Democratic-Republican | 1820 | Incumbent lost re-election. New member elected. Democratic-Republican hold. | |||||
| John Brown | Democratic-Republican | 1820 | Incumbent re-elected. | nowrap | ||||
| John Tod | Democratic-Republican | 1820 | Incumbent re-elected. | nowrap | ||||
| Andrew Stewart | Democratic-Republican | 1820 | Incumbent re-elected. | nowrap | ||||
| Thomas Patterson | Democratic-Republican | 1816 | Incumbent re-elected. | nowrap | ||||
| Walter Forward | Democratic-Republican | 1822 (Special) | New seat. New member elected. Democratic-Republican gain. | |||||
| None (District created) | New seat. New member elected. Democratic-Republican gain. | |||||||
| George Plumer | Democratic-Republican | 1820 | Incumbent re-elected. | nowrap | ||||
| Patrick Farrelly | Democratic-Republican | 1820 | Incumbent re-elected. | nowrap | ||||