| Election Name: | 1819 United States Senate elections in Maryland |
| Popular Vote1: | 49 |
| Colour1: | AACC99 |
| Percentage1: | 27.84% |
| Party1: | Democratic-Republican |
| Candidate1: | William Pinkney |
| Image1: | William Pinkney (NYPL Hades-256737-EM15101) (cropped).jpg |
| Popular Vote2: | 50 |
| Colour2: | AACC99 |
| Percentage2: | 28.41% |
| Party2: | Democratic-Republican |
| Candidate2: | Edward Lloyd |
| Next Year: | 1821 |
| Next Election: | 1821 United States Senate election in Maryland |
| Previous Year: | 1816 |
| Previous Election: | 1816 United States Senate special elections in Maryland |
| Votes For Election: | 80 members of the Maryland General Assembly |
| Vote Type: | Legislative |
| Election Date: | December 14, 1819 |
| Type: | presidential |
On April 23, 1819, incumbent Federalist senator Alexander Contee Hanson died. The other incumbent senator, Robert Henry Goldsborough, ran for re-election to hold his seat.The Maryland legislature elected a successor to finish Hanson's term, as well as a senator for the term for the other class. The two top vote-getters (both Democratic-Republicans) were declared the winners, with the first-place winner, Edward Lloyd taking the Class 3 seat, which ran March 4, 1819, to March 3, 1825. The second-place winner, William Pinkney, took the Class 1 seat, finishing Hanson's term which ran March 4, 1817, to March 3, 1823.