| Unit Name: | 10th Massachusetts Infantry Regiment |
| Dates: | June 21, 1861 – July 6, 1864 |
| Country: |  United States |
| Allegiance: | Union |
| Branch: | Infantry |
| Size: | 1,218 |
| Command Structure: | In 1862: 2nd Brigade (Devens's), 3rd Division (Newton's), VI Corps, Army of the Potomac |
| Disbanded: | July 6, 1864 |
| Commander1: | Henry Shaw Briggs |
| Commander1 Label: | Colonel |
| Commander2: | Henry L. Eustis |
| Commander2 Label: | Colonel |
| Identification Symbol Label: | VI Corps (3rd Division) badge |
The 10th Massachusetts Infantry Regiment was a regiment of infantry in the Union Army during the American Civil War. Organized at Hampden Park in Springfield, Massachusetts in the early summer of 1861 and consisting mostly of men from western Massachusetts, the regiment was mustered in on June 21, 1861. It was originally led by Colonel Henry Shaw Briggs, an attorney and prominent citizen of Pittsfield, Massachusetts.[1]