1-Bromododecane is a bromoalkane with the formula Br(CH2)11CH3. It is a colorless liquid. It is used as a long chain alkylating agent to improve the lipophilicity and hydrophobicity of organic molecules for biological applications.
Most 1-bromoalkanes are prepared by free-radical addition of hydrogen bromide to the 1-alkene, which is 1-dodecene in the case of 1-bromododecane. These conditions lead to anti-Markovnikov addition, giving the 1-bromo derivative.
1-Bromododecane can also be prepared by treating dodecanol with hydrobromic acid and sulfuric acid.[1]
CH3(CH2)11OH + HBr → CH3(CH2)11Br + H2O