1-Androstenedione Explained

1-Androstenedione, or 5α-androst-1-ene-3,17-dione, also known as 4,5α-dihydro-δ¹-4-androstenedione, is a synthetic androgen and anabolic steroid. It is a 5α-reduced isomer of the endogenous steroid 4-androstenedione and acts as an androgen prohormone of 1-testosterone (4,5α-dihydro-δ¹-testosterone), a derivative of dihydrotestosterone (DHT).^[1]

1-Androstenedione is on the World Anti-Doping Agency's list of prohibited substances,^[2] and is therefore banned from use in most major sports.

See also

• 1-Androstenediol

Notes and References

1. Zhang H, Qiu Z . An efficient synthesis of 5α-androst-1-ene-3,17-dione . Steroids . 71 . 13–14 . 1088–90 . 17123559 . 10.1016/j.steroids.2006.09.008. December 2006. 53258890 .
2. Web site: The World Anti-Doping Code: The 2012 Prohibited List . . 2012-07-17 . https://web.archive.org/web/20120513020202/http://www.wada-ama.org/Documents/World_Anti-Doping_Program/WADP-Prohibited-list/2012/WADA_Prohibited_List_2012_EN.pdf . 2012-05-13 . dead .