1,4-Dimethoxybenzene is an organic compound with the formula CH(OCH). It is one of three isomers of dimethoxybenzene. It is a white solid with an intensely sweet floral odor. It is produced by several plant species.[1]
It occurs naturally in willow (Salix), tea, hyacinth, zucchini (Cucurbita pepo).[1] It appears to attract bees as it has a powerful response in their antenna.[2] In a study in mice, Iranian scientists identified 1,4-dimethoxybenzene as the major psychoactive chemical in musk willow (Salix aegyptiaca) by its ability to cause somnolescence and depressed activity.[3]
It is produced by the methylation of hydroquinone using dimethylsulfate and an alkali.
1,4-Dimethoxybenzene is mainly used in perfumes and soaps.[1]
It is an intermediate in synthesis of organic compounds, including pharmaceuticals such as methoxamine and butaxamine.
It can be used as a developer in black and white film, and as a base in synthesizing catecholamines and phenethylamines.