1,2-dihydroxynaphthalene dioxygenase explained

1,2-dihydroxynaphthalene dioxygenase
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1,2-dihydroxynaphthalene dioxygenase (1,2-DHN dioxygenase, DHNDO, 1,2-dihydroxynaphthalene oxygenase, 1,2-dihydroxynaphthalene:oxygen oxidoreductase) is an enzyme with systematic name naphthalene-1,2-diol:oxygen oxidoreductase.[1] [2] [3] This enzyme catalyses the following chemical reaction

naphthalene-1,2-diol + O2

\rightleftharpoons

2-hydroxy-2H-chromene-2-carboxylate

This enzyme is involved in naphthalene degradation.

Notes and References

  1. Kuhm AE, Stolz A, Ngai KL, Knackmuss HJ . Purification and characterization of a 1,2-dihydroxynaphthalene dioxygenase from a bacterium that degrades naphthalenesulfonic acids . Journal of Bacteriology . 173 . 12 . 3795–802 . June 1991 . 2050635 . 208010 .
  2. Keck A, Conradt D, Mahler A, Stolz A, Mattes R, Klein J . Identification and functional analysis of the genes for naphthalenesulfonate catabolism by Sphingomonas xenophaga BN6 . Microbiology . 152 . Pt 7 . 1929–40 . July 2006 . 16804169 . 10.1099/mic.0.28783-0 . free .
  3. Patel TR, Barnsley EA . Naphthalene metabolism by pseudomonads: purification and properties of 1,2-dihydroxynaphthalene oxygenase . Journal of Bacteriology . 143 . 2 . 668–73 . August 1980 . 7204331 . 294337 .

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