| [tyrosine 3-monooxygenase] kinase | |
| Ec Number: | 2.7.11.6 |
| Cas Number: | 103537-12-8 |
| Go Code: | 0050369 |
In enzymology, a [tyrosine 3-monooxygenase] kinase is an enzyme that catalyzes the chemical reaction
ATP + [tyrosine-3-monooxygenase]
\rightleftharpoons
Thus, the two substrates of this enzyme are ATP and tyrosine 3-monooxygenase, whereas its two products are ADP and phospho-(tyrosine-3-monooxygenase).
This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases). The systematic name of this enzyme class is ATP:[tyrosine-3-monoxygenase] phosphotransferase. Other names in common use include pheochromocytoma tyrosine hydroxylase-associated kinase, STK4, and tyrosine 3-monooxygenase kinase (phosphorylating). This enzyme participates in MAPK signaling pathway and non-small cell lung cancer.