(S)-beta-macrocarpene synthase explained

(S)-β-Macrocarpene synthase
Ec Number:	5.5.1.17

(S)-β-macrocarpene synthase (TPS6, TPS11) is an enzyme with systematic name (S)-β-macrocarpene lyase (decyclizing).^[1] This enzyme catalyses the following chemical reaction

(S)-β-bisabolene

\rightleftharpoons (S)-β-macrocarpene

The synthesis of (S)-beta-macrocarpene from (2E,6E)-farnesyl diphosphate proceeds in two steps.

Notes and References

1. Köllner TG, Schnee C, Li S, Svatos A, Schneider B, Gershenzon J, Degenhardt J . Protonation of a neutral (S)-beta-bisabolene intermediate is involved in (S)-β-macrocarpene formation by the maize sesquiterpene synthases TPS6 and TPS11 . The Journal of Biological Chemistry . 283 . 30 . 20779–88 . July 2008 . 18524777 . 3258946 . 10.1074/jbc.m802682200 . free .