(S)-1-phenylethanol dehydrogenase explained

(S)-1-phenylethanol dehydrogenase
Ec Number:	1.1.1.311

(S)-1-phenylethanol dehydrogenase (PED) is an enzyme with systematic name (S)-1-phenylethanol:NAD⁺ oxidoreductase.^{[1] [2]} This enzyme catalyses the following chemical reaction

(S)-1-phenylethanol + NAD⁺

\rightleftharpoons acetophenone + NADH + H⁺

The enzyme is involved in degradation of ethylbenzene.

Notes and References

1. Kniemeyer O, Heider J . (S)-1-phenylethanol dehydrogenase of Azoarcus sp. strain EbN1, an enzyme of anaerobic ethylbenzene catabolism . Archives of Microbiology . 176 . 1-2 . 129–35 . July 2001 . 11479712 . 10.1007/s002030100303 .
2. Höffken HW, Duong M, Friedrich T, Breuer M, Hauer B, Reinhardt R, Rabus R, Heider J . Crystal structure and enzyme kinetics of the (S)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain EbN1 . Biochemistry . 45 . 1 . 82–93 . January 2006 . 16388583 . 10.1021/bi051596b .