(RS)-norcoclaurine 6-O-methyltransferase explained
| (RS)-norcoclaurine 6-O-methyltransferase |
| Ec Number: | 2.1.1.128 |
| Cas Number: | 167398-06-3 |
| Go Code: | 0030786 |
In enzymology, a (RS)-norcoclaurine 6-O-methyltransferase is an enzyme that catalyzes the chemical reaction
S-adenosyl-L-methionine + (RS)-norcoclaurine
S-adenosyl-L-homocysteine + (RS)-coclaurine
Thus, the two substrates of this enzyme are S-adenosyl methionine and (R,S)-norcoclaurine, whereas its two products are S-adenosylhomocysteine and (R,S)-coclaurine.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:(RS)-norcoclaurine 6-O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.
References
- Rueffer M, Nagakura N, Zenk MH . 1983 . Partial purification and properties of S-adenosyl-L-methionine:(R),(S)-norlaudanosoline-6-O-methyltransferase from Argemone platyceras cell cultures . Planta Med. . 49 . 131 - 137 . 10.1055/s-2007-969833 . 17405035 . 11 .
- Sato F, Tsujita T, Katagiri Y, Yoshida S, Yamada Y . 1994 . Purification and characterization of S-adenosyl-L-methionine: norcoclaurine 6-O-methyltransferase from cultured Coptis japonica cells . Eur. J. Biochem. . 225 . 125 - 31 . 7925429 . 10.1111/j.1432-1033.1994.00125.x . 1 . free .
- Stadler R, Zenk MH . 1990 . A revision of the generally accepted pathway for the biosynthesis of the benzyltetrahydroisoquinoline reticuline . Liebigs Ann. . Chem. . 555 - 562 . 10.1002/jlac.1990199001104 .
